Isaac married Louisa Ann Yazell in 1909. Louisa (daughter of Daniel Combs Yazell and Alice Humphries) was born on 5 Mar 1844 in Fleming County, Kentucky, United States; died on 21 Aug 1933 in Tilton, Fleming, Kentucky, United States; was buried on 23 Aug 1933 in Concord, Fleming, Kentucky, United States. [Group Sheet] [Family Chart]